| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50291068 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157558 |
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| Ki | 2.3±n/a nM |
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| Citation |  Schwartz, TM; Bundy, GL; Strohbach, JW; Thaisrivongs, S; Johnson, PD; Skulnick, HI; Tomich, PK; Lynn, JC; Chong, KT; Hinshaw, RR; Raub, TJ; Padbury, GE; Toth, LN Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors Bioorg Med Chem Lett7:399-402 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM50291068 |
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| n/a |
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| Name | BDBM50291068 |
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| Synonyms: | 6-(2-Cyclopropyl-1-cyclopropylmethyl-ethyl)-3-{cyclopropyl-[3-(pyridine-2-sulfonylmethyl)-phenyl]-methyl}-4-hydroxy-pyran-2-one | CHEMBL127219 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H33NO5S |
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| Mol. Mass. | 519.652 |
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| SMILES | Oc1cc(oc(=O)c1C(C1CC1)c1cccc(CS(=O)(=O)c2ccccn2)c1)C(CC1CC1)CC1CC1 |
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| Structure | 
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