| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50291395 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_139972 |
|---|
| Ki | 129±n/a nM |
|---|
| Citation |  Kassiou, M; Read, RW; Shi, Xq Synthesis and evaluation of halogenated dibenzodiazepines as muscarinic receptor ligands Bioorg Med Chem Lett7:799-804 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50291395 |
|---|
| n/a |
|---|
| Name | BDBM50291395 |
|---|
| Synonyms: | CHEMBL168149 | N-Ethyl-4-fluoro-N-[4-(1-{2-[10-(4-fluoro-benzoyl)-11-oxo-10,11-dihydro-dibenzo[b,e][1,4]diazepin-5-yl]-2-oxo-ethyl}-piperidin-4-yl)-butyl]-benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C40H40F2N4O4 |
|---|
| Mol. Mass. | 678.7668 |
|---|
| SMILES | CCN(CCCCC1CCN(CC(=O)N2c3ccccc3N(C(=O)c3ccc(F)cc3)C(=O)c3ccccc23)CC1)C(=O)c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
