| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
|---|
| Ligand | BDBM50291394 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_140121 |
|---|
| Ki | 32±n/a nM |
|---|
| Citation |  Kassiou, M; Read, RW; Shi, Xq Synthesis and evaluation of halogenated dibenzodiazepines as muscarinic receptor ligands Bioorg Med Chem Lett7:799-804 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M2 |
|---|
| Name: | Muscarinic acetylcholine receptor M2 |
|---|
| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
|---|
| Type: | GPCR |
|---|
| Mol. Mass.: | 51730.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08172 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
|
|
|---|
| BDBM50291394 |
|---|
| n/a |
|---|
| Name | BDBM50291394 |
|---|
| Synonyms: | CHEMBL353140 | N-Ethyl-4-fluoro-N-(4-{1-[2-oxo-2-(11-oxo-10,11-dihydro-dibenzo[b,e][1,4]diazepin-5-yl)-ethyl]-piperidin-4-yl}-butyl)-benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H37FN4O3 |
|---|
| Mol. Mass. | 556.6703 |
|---|
| SMILES | CCN(CCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1)C(=O)c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
