| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50292904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_494629 (CHEMBL945288) |
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| Ki | 21±n/a nM |
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| Citation |  Tu, Z; Efange, SM; Xu, J; Li, S; Jones, LA; Parsons, SM; Mach, RH Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. J Med Chem52:1358-69 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50292904 |
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| n/a |
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| Name | BDBM50292904 |
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| Synonyms: | (1R,2R,5R)-5-(4-fluorobenzyloxy)-2-(4-phenylpiperidin-1-yl)cyclohexanol | CHEMBL516814 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30FNO2 |
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| Mol. Mass. | 383.4989 |
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| SMILES | O[C@@H]1C[C@@H](CC[C@H]1N1CCC(CC1)c1ccccc1)OCc1ccc(F)cc1 |r| |
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| Structure | 
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