| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50293491 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_570543 (CHEMBL1026915) |
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| IC50 | 379±n/a nM |
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| Citation |  Cameron, KO; Lefker, BA; Ke, HZ; Li, M; Zawistoski, MP; Tjoa, CM; Wright, AS; DeNinno, SL; Paralkar, VM; Owen, TA; Yu, L; Thompson, DD Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorg Med Chem Lett19:2075-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_RAT | Prostanoid EP2 receptor | Ptger2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39786.37 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1501400 |
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| Residue: | 357 |
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| Sequence: | MDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAG
SRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFF
SLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYV
QYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGS
SLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRA
LRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL
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| BDBM50293491 |
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| n/a |
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| Name | BDBM50293491 |
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| Synonyms: | 3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)methyl)phenyl)propanoic acid | CHEMBL556333 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29NO4S |
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| Mol. Mass. | 403.535 |
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| SMILES | CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 |
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| Structure | 
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