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TargetD(3) dopamine receptor
LigandBDBM50119375
Substrate/Competitorn/a
Meas. Tech.ChEMBL_570886
Ki 150±n/a nM
Citation Ehrlich KGötz ABollinger STschammer NBettinetti LHärterich SHübner HLanig HGmeiner P Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding. J Med Chem 52:4923-35 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(3) dopamine receptor
Name:D(3) dopamine receptor
Synonyms:D2-like dopamine receptor | DOPAMINE D3 | DRD3 | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:n/a
Mol. Mass.:44243.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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  Blast E-value cutoff:
BDBM50119375
n/a
NameBDBM50119375
Synonyms:CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)H-pyrazolo[1,5-a]pyridine-3-carboxamide | Pyrazolo[1,5-a]pyridine-3-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide
TypeSmall organic molecule
Emp. Form.C22H27N5O2
Mol. Mass.393.4821
SMILESCOc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1
Structure
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