| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50294520 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_575570 (CHEMBL1036413) |
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| Ki | 80±n/a nM |
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| Citation |  Gillespie, RJ; Bamford, SJ; Gaur, S; Jordan, AM; Lerpiniere, J; Mansell, HL; Stratton, GC Antagonists of the human A(2A) receptor. Part 5: Highly bio-available pyrimidine-4-carboxamides. Bioorg Med Chem Lett19:2664-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50294520 |
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| n/a |
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| Name | BDBM50294520 |
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| Synonyms: | 2-amino-N-(4-chlorobenzyl)-6-(furan-2-yl)pyrimidine-4-carboxamide | CHEMBL552511 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13ClN4O2 |
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| Mol. Mass. | 328.753 |
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| SMILES | Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1ccc(Cl)cc1 |
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| Structure | 
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