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TargetHeat shock factor protein 1
LigandBDBM50295794
Substrate/Competitorn/a
Meas. Tech.ChEMBL_578167 (CHEMBL1060467)
EC50 41600±n/a nM
Citation Zhou, YVu, KChen, YPham, JBrady, TLiu, GChen, JNam, JMurali Mohan Reddy, PSAu, QYoon, ISTremblay, MHYip, GCher, CZhang, BBarber, JRNg, SC Chloro-oxime derivatives as novel small molecule chaperone amplifiers. Bioorg Med Chem Lett19:3128-35 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Heat shock factor protein 1
Name:Heat shock factor protein 1
Synonyms:HSF1 | HSF1_HUMAN | HSTF1
Type:PROTEIN
Mol. Mass.:57244.20
Organism:Homo sapiens (Human)
Description:ChEMBL_1512556
Residue:529
Sequence:
MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS
VDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50295794
n/a
NameBDBM50295794
Synonyms:6-(N,N-dimethylsulfamoyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride | CHEMBL551056
TypeSmall organic molecule
Emp. Form.C18H25ClN4O5S
Mol. Mass.444.933
SMILESCN(C)S(=O)(=O)c1ccc2nc(oc2c1)C(\Cl)=N\OCC(O)CN1CCCCC1
Structure
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