| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
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| Ligand | BDBM50295795 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_578167 (CHEMBL1060467) |
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| EC50 | 42900±n/a nM |
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| Citation |  Zhou, Y; Vu, K; Chen, Y; Pham, J; Brady, T; Liu, G; Chen, J; Nam, J; Murali Mohan Reddy, PS; Au, Q; Yoon, IS; Tremblay, MH; Yip, G; Cher, C; Zhang, B; Barber, JR; Ng, SC Chloro-oxime derivatives as novel small molecule chaperone amplifiers. Bioorg Med Chem Lett19:3128-35 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heat shock factor protein 1 |
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| Name: | Heat shock factor protein 1 |
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| Synonyms: | HSF1 | HSF1_HUMAN | HSTF1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57244.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1512556 |
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| Residue: | 529 |
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| Sequence: | MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS
VDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
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| BDBM50295795 |
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| n/a |
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| Name | BDBM50295795 |
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| Synonyms: | 5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride | CHEMBL561378 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24ClN3O5S |
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| Mol. Mass. | 429.918 |
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| SMILES | CCS(=O)(=O)c1ccc2oc(nc2c1)C(\Cl)=N\OCC(O)CN1CCCCC1 |
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| Structure | 
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