| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50295868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_578610 (CHEMBL1054749) |
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| IC50 | 8080±n/a nM |
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| Citation |  Crepaldi, P; Cacciari, B; Bonache, MC; Spalluto, G; Varani, K; Borea, PA; Kügelgen, I; Hoffmann, K; Pugliano, M; Razzari, C; Cattaneo, M 6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors. Bioorg Med Chem17:4612-21 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50295868 |
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| n/a |
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| Name | BDBM50295868 |
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| Synonyms: | CHEMBL562982 | Toluene-4-sulfonic acid 6-amino-2-(2-aminoethylsulfanyl)-pyrimidin-4-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N4O3S2 |
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| Mol. Mass. | 340.421 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)Oc1cc(N)nc(SCCN)n1 |
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| Structure | 
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