| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B |
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| Ligand | BDBM50296420 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_580786 (CHEMBL1059768) |
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| Ki | 11900±n/a nM |
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| Citation |  Fernández, D; Avilés, FX; Vendrell, J A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases. Eur J Med Chem44:3266-71 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B |
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| Name: | Carboxypeptidase B |
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| Synonyms: | CPB |
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| Type: | Enzyme |
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| Mol. Mass.: | 48382.46 |
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| Organism: | Helicoverpa zea (Corn earworm moth) (Heliothis zea) |
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| Description: | Q3T905 |
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| Residue: | 429 |
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| Sequence: | MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREG
VVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYD
NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGG
IHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRS
TNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLA
RMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSA
LVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGA
RRAGDLFRK
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| BDBM50296420 |
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| n/a |
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| Name | BDBM50296420 |
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| Synonyms: | CHEMBL558714 | ethyl 2-(4-ethyl-5-((4-ethylphenoxy)methyl)-4H-1,2,4-triazol-3-ylthio)-3-methylbutanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29N3O3S |
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| Mol. Mass. | 391.528 |
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| SMILES | CCOC(=O)C(Sc1nnc(COc2ccc(CC)cc2)n1CC)C(C)C |
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| Structure | 
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