| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxypeptidase B |
|---|
| Ligand | BDBM50296425 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_580786 (CHEMBL1059768) |
|---|
| Ki | 18000±n/a nM |
|---|
| Citation |  Fernández, D; Avilés, FX; Vendrell, J A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases. Eur J Med Chem44:3266-71 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxypeptidase B |
|---|
| Name: | Carboxypeptidase B |
|---|
| Synonyms: | CPB |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48382.46 |
|---|
| Organism: | Helicoverpa zea (Corn earworm moth) (Heliothis zea) |
|---|
| Description: | Q3T905 |
|---|
| Residue: | 429 |
|---|
| Sequence: | MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREG
VVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYD
NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGG
IHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRS
TNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLA
RMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSA
LVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGA
RRAGDLFRK
|
|
|
|---|
| BDBM50296425 |
|---|
| n/a |
|---|
| Name | BDBM50296425 |
|---|
| Synonyms: | 2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-yl)ethanone | CHEMBL550115 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N4O3S |
|---|
| Mol. Mass. | 388.484 |
|---|
| SMILES | Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1 |
|---|
| Structure | 
|
|---|
Search and Browse
