| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50299281 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_589788 (CHEMBL1051411) |
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| Ki | 8.2±n/a nM |
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| Citation |  Maestrup, EG; Fischer, S; Wiese, C; Schepmann, D; Hiller, A; Deuther-Conrad, W; Steinbach, J; Wünsch, B; Brust, P Evaluation of spirocyclic 3-(3-fluoropropyl)-2-benzofurans as sigma1 receptor ligands for neuroimaging with positron emission tomography. J Med Chem52:6062-72 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50299281 |
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| n/a |
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| Name | BDBM50299281 |
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| Synonyms: | CHEMBL582996 | [3-(1'-Benzyl-3H-spiro[[2]benzofuran-1,4'-piperidin]-3-yl)propyl]p-toluenesulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33NO4S |
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| Mol. Mass. | 491.642 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)OCCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12 |
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| Structure | 
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