| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50300166 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_594168 (CHEMBL1039598) |
|---|
| Ki | 1070±n/a nM |
|---|
| Citation |  Frecentese, F; Fiorino, F; Perissutti, E; Severino, B; Magli, E; Esposito, A; De Angelis, F; Massarelli, P; Nencini, C; Viti, B; Santagada, V; Caliendo, G Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands. Eur J Med Chem45:752-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM50300166 |
|---|
| n/a |
|---|
| Name | BDBM50300166 |
|---|
| Synonyms: | CHEMBL566533 | Ethyl 5-(3-(4-(3-chlorophenyl)piperazin-1-yl)propoxy)-1Hindole-2-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H28ClN3O3 |
|---|
| Mol. Mass. | 441.95 |
|---|
| SMILES | CCOC(=O)c1cc2cc(OCCCN3CCN(CC3)c3cccc(Cl)c3)ccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
