| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50300362 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_591224 (CHEMBL1059302) |
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| IC50 | 12±n/a nM |
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| Citation |  Sinha, B; Cao, Z; Murray, TF; Aldrich, JV Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors. J Med Chem52:7372-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50300362 |
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| n/a |
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| Name | BDBM50300362 |
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| Synonyms: | (S)-2-amino-3-(4-hydroxyphenyl)-N-((S)-1-(2-((S)-1-((S)-4-methyl-1-((3-nitropyridin-2-yl)disulfanyl)pentan-2-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-2-oxoethylamino)-1-oxopropan-2-yl)propanamide | CHEMBL573688 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H43N7O7S2 |
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| Mol. Mass. | 725.878 |
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| SMILES | CC(C)C[C@@H](CSSc1ncccc1[N+]([O-])=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| |
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| Structure | 
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