| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50301206 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598772 (CHEMBL1042012) |
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| IC50 | 1.7±n/a nM |
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| Citation |  Kameda, M; Ando, M; Nakama, C; Kobayashi, K; Kawamoto, H; Ito, S; Suzuki, T; Tani, T; Ozaki, S; Tokita, S; Sato, N Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors. Bioorg Med Chem Lett19:5124-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50301206 |
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| n/a |
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| Name | BDBM50301206 |
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| Synonyms: | CHEMBL566889 | [6-(4,5-Dimethyl-oxazol-2-ylsulfanylmethyl)-4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-pyridin-2-yl]-(6-methyl-pyridin-2-ylmethyl)-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N5O3S2 |
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| Mol. Mass. | 473.611 |
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| SMILES | Cc1nc(SCc2cc(cc(NCc3cccc(C)n3)n2)N2CCS(=O)(=O)CC2)oc1C |
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| Structure | 
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