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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2C | ||
| Ligand | BDBM50301504 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_600347 (CHEMBL1041065) | ||
| Ki | 9±n/a nM | ||
| Citation |  Dosa, PI; Strah-Pleynet, S; Jayakumar, H; Casper, M; Decaire, M; Xiong, Y; Lehmann, J; Choi, K; Elwell, K; Wong, A; Webb, RR; Adams, JW; Ramirez, J; Richman, JG; Thomsen, W; Semple, G; Teegarden, BR Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents. Bioorg Med Chem Lett19:5486-9 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2C | |||
| Name: | 5-hydroxytryptamine receptor 2C | ||
| Synonyms: | 5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 51836.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28335 | ||
| Residue: | 458 | ||
| Sequence: |
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| BDBM50301504 | |||
| n/a | |||
| Name | BDBM50301504 | ||
| Synonyms: | 1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-fluorophenyl)urea | CHEMBL583624 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H25BrFN5O2 | ||
| Mol. Mass. | 502.379 | ||
| SMILES | Cn1ncc(Br)c1-c1cc(NC(=O)Nc2ccc(F)cc2)ccc1OCCN1CCCC1 |(28.29,-24.64,;28.25,-26.18,;29.48,-27.11,;28.97,-28.57,;27.43,-28.53,;26.5,-29.76,;26.99,-27.06,;25.54,-26.54,;24.21,-27.31,;22.88,-26.54,;21.55,-27.31,;20.21,-26.54,;20.21,-25,;18.88,-27.32,;17.55,-26.55,;16.21,-27.32,;14.87,-26.55,;14.88,-25.01,;13.54,-24.24,;16.21,-24.23,;17.54,-25,;22.87,-25.01,;24.2,-24.23,;25.54,-25,;26.87,-24.22,;26.87,-22.68,;28.2,-21.91,;29.54,-22.68,;29.71,-24.2,;31.22,-24.51,;31.98,-23.18,;30.95,-22.04,)| | ||
| Structure | 
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