| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled estrogen receptor 1 |
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| Ligand | BDBM50303804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_594736 (CHEMBL1038026) |
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| IC50 | 20±n/a nM |
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| Citation |  Ramesh, C; Nayak, TK; Burai, R; Dennis, MK; Hathaway, HJ; Sklar, LA; Prossnitz, ER; Arterburn, JB Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30. J Med Chem53:1004-14 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled estrogen receptor 1 |
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| Name: | G-protein coupled estrogen receptor 1 |
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| Synonyms: | CEPR | CMKRL2 | DRY12 | G-protein coupled estrogen receptor 1 | G-protein-coupled receptor (GPR30 ) | GPER | GPER1 | GPER1_HUMAN | GPR30 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42259.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_982507 |
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| Residue: | 375 |
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| Sequence: | MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
PDSTEQSDVRFSSAV
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| BDBM50303804 |
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| n/a |
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| Name | BDBM50303804 |
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| Synonyms: | (3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline | CHEMBL583543 | cid_3136844 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16BrNO2 |
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| Mol. Mass. | 370.24 |
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| SMILES | Brc1cc2OCOc2cc1[C@@H]1Nc2ccccc2[C@@H]2C=CC[C@H]12 |r,c:22| |
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| Structure | 
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