| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM50305386 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_603589 (CHEMBL1071141) |
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| EC50 | >10000±n/a nM |
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| Citation |  Zécri, FJ; Albert, R; Landrum, G; Hinterding, K; Cooke, NG; Guerini, D; Streiff, M; Bruns, C; Nuesslein-Hildesheim, B Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P(1)) receptor agonists. Bioorg Med Chem Lett20:35-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM50305386 |
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| n/a |
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| Name | BDBM50305386 |
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| Synonyms: | 1-((3bS,4aR)-3,4,4-Trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-heptan-1-one | CHEMBL596053 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H26N2O |
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| Mol. Mass. | 274.4011 |
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| SMILES | CCCCCCC(=O)n1nc(C)c2[C@H]3[C@@H](Cc12)C3(C)C |r| |
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| Structure | 
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