| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50308565 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613655 (CHEMBL1066998) |
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| Ki | 5000±n/a nM |
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| Citation |  Hierrezuelo, J; Manuel López-Romero, J; Rico, R; Brea, J; Isabel Loza, M; Cai, C; Algarra, M Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors. Bioorg Med Chem18:2081-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50308565 |
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| n/a |
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| Name | BDBM50308565 |
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| Synonyms: | 7-(3,6,9,12-tetraoxatricos-22-enyl)theophylline | CHEMBL591242 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H44N4O6 |
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| Mol. Mass. | 508.6508 |
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| SMILES | Cn1c2ncn(CCOCCOCCOCCOCCCCCCCCCC=C)c2c(=O)n(C)c1=O |
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| Structure | 
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