| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Granulocyte colony-stimulating factor receptor |
|---|
| Ligand | BDBM50309396 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_609463 (CHEMBL1069757) |
|---|
| Kd | 47000±n/a nM |
|---|
| Citation |  El-Haggar, R; Kamikawa, K; Machi, K; Ye, Z; Ishino, Y; Tsumuraya, T; Fujii, I Molecular design of small organic molecules based on structural information for a conformationally constrained peptide that binds to G-CSF receptor. Bioorg Med Chem Lett20:1169-72 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Granulocyte colony-stimulating factor receptor |
|---|
| Name: | Granulocyte colony-stimulating factor receptor |
|---|
| Synonyms: | CD_antigen=CD114 | CSF3R | CSF3R_HUMAN | G-CSF-R | GCSFR | Granulocyte colony stimulating factor receptor | Granulocyte colony-stimulating factor receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 92149.36 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_609463 |
|---|
| Residue: | 836 |
|---|
| Sequence: | MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQ
ILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAG
YPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPK
DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPE
AAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPA
TAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQLFWKPVP
LEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT
PVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRME
QNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGK
TWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHL
MAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWP
SVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGL
PTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGL
TPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF
|
|
|
|---|
| BDBM50309396 |
|---|
| n/a |
|---|
| Name | BDBM50309396 |
|---|
| Synonyms: | 3-((3-(3-amino-3-oxopropyl)phenyl)(3-(3-aminopropoxy)-5-(isopentyloxy)benzyl)amino)propanoic acid | CHEMBL590814 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H39N3O5 |
|---|
| Mol. Mass. | 485.6157 |
|---|
| SMILES | CC(C)CCOc1cc(CN(CCC(O)=O)c2cccc(CCC(N)=O)c2)cc(OCCCN)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
