| Reaction Details |
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 | Report a problem with these data |
| Target | Granulocyte colony-stimulating factor receptor |
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| Ligand | BDBM50309397 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_609463 (CHEMBL1069757) |
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| Kd | 20000±n/a nM |
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| Citation |  El-Haggar, R; Kamikawa, K; Machi, K; Ye, Z; Ishino, Y; Tsumuraya, T; Fujii, I Molecular design of small organic molecules based on structural information for a conformationally constrained peptide that binds to G-CSF receptor. Bioorg Med Chem Lett20:1169-72 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Granulocyte colony-stimulating factor receptor |
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| Name: | Granulocyte colony-stimulating factor receptor |
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| Synonyms: | CD_antigen=CD114 | CSF3R | CSF3R_HUMAN | G-CSF-R | GCSFR | Granulocyte colony stimulating factor receptor | Granulocyte colony-stimulating factor receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 92149.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_609463 |
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| Residue: | 836 |
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| Sequence: | MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQ
ILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAG
YPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPK
DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPE
AAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPA
TAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQLFWKPVP
LEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT
PVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRME
QNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGK
TWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHL
MAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWP
SVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGL
PTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGL
TPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF
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| BDBM50309397 |
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| n/a |
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| Name | BDBM50309397 |
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| Synonyms: | 3-(3-(3-amino-3-oxopropyl)-3'-(3-aminopropoxy)-5'-(isopentyloxy)biphenyl-4-yl)propanoic acid | CHEMBL602139 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H36N2O5 |
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| Mol. Mass. | 456.5744 |
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| SMILES | CC(C)CCOc1cc(OCCCN)cc(c1)-c1ccc(CCC(O)=O)c(CCC(N)=O)c1 |
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| Structure | 
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