Reaction Details | |||
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Target | Melanocortin receptor 5 | ||
Ligand | BDBM50310319 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_608235 (CHEMBL1072424) | ||
EC50 | 2950±n/a nM | ||
Citation | Ovadia, O; Linde, Y; Haskell-Luevano, C; Dirain, ML; Sheynis, T; Jelinek, R; Gilon, C; Hoffman, A The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm. Bioorg Med Chem18:580-9 (2010) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 5 | |||
Name: | Melanocortin receptor 5 | ||
Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36966.58 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P41149 | ||
Residue: | 325 | ||
Sequence: |
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BDBM50310319 | |||
n/a | |||
Name | BDBM50310319 | ||
Synonyms: | 2-((6S,9S)-6-((1H-indol-3-yl)methyl)-13,16-dibenzyl-9-(3-guanidinopropyl)-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexaazacycloicosan-4-yl)acetamide | CHEMBL602653 | ||
Type | Small organic molecule | ||
Emp. Form. | C43H53N11O7 | ||
Mol. Mass. | 835.9504 | ||
SMILES | NC(=O)CN1CCNC(=O)CCC(=O)N(Cc2ccccc2)CC(=O)N(Cc2ccccc2)CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C1=O |r,wU:37.39,wD:48.50,(37.65,-41.43,;36.31,-42.2,;36.32,-43.74,;34.98,-41.43,;33.66,-42.2,;32.32,-41.43,;32.31,-39.89,;28.27,-39.09,;28.26,-37.55,;29.59,-36.77,;26.92,-36.78,;25.59,-37.57,;25.6,-39.11,;26.94,-39.86,;24.27,-39.88,;22.94,-39.13,;22.93,-37.59,;24.26,-36.81,;24.25,-35.27,;22.91,-34.5,;21.58,-35.3,;21.59,-36.83,;24.28,-41.43,;22.95,-42.21,;21.62,-41.44,;22.96,-43.75,;21.64,-44.52,;20.3,-43.75,;20.3,-42.22,;18.96,-41.44,;17.63,-42.22,;17.64,-43.77,;18.97,-44.53,;24.31,-44.53,;25.65,-43.76,;25.65,-42.22,;26.98,-44.53,;28.32,-43.76,;28.32,-45.3,;26.99,-46.07,;26.99,-47.61,;25.65,-48.38,;25.65,-49.92,;24.31,-50.69,;26.99,-50.69,;29.65,-44.53,;29.65,-46.07,;30.98,-43.76,;32.32,-44.53,;32.32,-46.07,;33.66,-46.83,;34.89,-45.9,;36.16,-46.79,;35.71,-48.26,;36.5,-49.57,;35.76,-50.91,;34.22,-50.94,;33.42,-49.63,;34.17,-48.28,;33.66,-43.74,;34.99,-44.51,)| | ||
Structure |