Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Melanocortin receptor 5 | ||
Ligand | BDBM50310322 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_608235 (CHEMBL1072424) | ||
EC50 | 16±n/a nM | ||
Citation | Ovadia, O; Linde, Y; Haskell-Luevano, C; Dirain, ML; Sheynis, T; Jelinek, R; Gilon, C; Hoffman, A The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm. Bioorg Med Chem18:580-9 (2010) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 5 | |||
Name: | Melanocortin receptor 5 | ||
Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36966.58 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P41149 | ||
Residue: | 325 | ||
Sequence: |
| ||
BDBM50310322 | |||
n/a | |||
Name | BDBM50310322 | ||
Synonyms: | (S)-2-(2-((S)-2-(2-acetamidoacetamido)-N-benzyl-3-phenylpropanamido)acetamido)-N-((S)-1-(2-amino-2-oxoethylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide | CHEMBL602651 | ||
Type | Small organic molecule | ||
Emp. Form. | C41H51N11O7 | ||
Mol. Mass. | 809.9131 | ||
SMILES | CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1 |r,wU:23.23,8.7,wD:34.34,(23.52,-9.64,;24.85,-10.41,;24.85,-11.95,;26.18,-9.64,;27.52,-10.41,;28.85,-9.64,;28.85,-8.1,;30.18,-10.41,;31.52,-9.64,;31.52,-8.09,;30.75,-6.75,;31.53,-5.42,;30.77,-4.08,;29.22,-4.07,;28.44,-5.42,;29.22,-6.75,;32.85,-10.41,;32.85,-11.95,;34.19,-9.64,;35.52,-10.41,;36.85,-9.64,;36.85,-8.1,;38.19,-10.41,;39.52,-9.64,;39.52,-8.1,;40.85,-7.33,;40.85,-5.79,;42.19,-5.02,;42.19,-3.48,;43.52,-2.71,;40.85,-2.71,;40.85,-10.41,;40.85,-11.95,;42.19,-9.64,;43.52,-10.41,;43.52,-11.95,;44.86,-12.72,;46.09,-11.78,;47.36,-12.66,;46.91,-14.13,;47.7,-15.44,;46.97,-16.79,;45.42,-16.82,;44.63,-15.5,;45.37,-14.16,;44.86,-9.64,;44.86,-8.1,;46.19,-10.41,;47.52,-9.64,;48.86,-10.41,;50.19,-9.64,;48.86,-11.95,;34.18,-8.09,;34.94,-6.75,;36.48,-6.75,;37.24,-5.41,;36.46,-4.08,;34.92,-4.09,;34.16,-5.43,)| | ||
Structure |