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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM50311482 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_622957 (CHEMBL1112209) | ||
| Ki | 295±n/a nM | ||
| Citation |  Palin, R; Clark, JK; Evans, L; Feilden, H; Fletcher, D; Hamilton, NM; Houghton, AK; Jones, PS; McArthur, D; Montgomery, B; Ratcliffe, PD; Smith, AR; Sutherland, A; Weston, MA; Wishart, G Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. Bioorg Med Chem Lett19:6441-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
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| BDBM50311482 | |||
| n/a | |||
| Name | BDBM50311482 | ||
| Synonyms: | 2-(1'-(4-tert-butylcyclohexyl)-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide | CHEMBL1079418 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H37N3O3 | ||
| Mol. Mass. | 427.5796 | ||
| SMILES | CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)(C)C)c2ccccc12 |(6.46,-42.43,;5.12,-41.66,;3.79,-42.42,;3.78,-43.96,;2.46,-41.65,;1.12,-42.42,;-.2,-41.65,;-.2,-40.11,;-1.52,-42.41,;-1.53,-43.94,;-2.87,-43.17,;-4.2,-43.94,;-4.2,-45.48,;-2.86,-46.25,;-1.52,-45.48,;-5.53,-46.25,;-6.88,-45.47,;-8.21,-46.24,;-8.21,-47.78,;-6.88,-48.55,;-5.54,-47.79,;-9.54,-48.54,;-10.87,-47.77,;-9.54,-50.08,;-9.94,-47.06,;-.2,-44.7,;-.21,-46.24,;1.13,-47.01,;2.46,-46.24,;2.46,-44.69,;1.12,-43.94,)| | ||
| Structure | 
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