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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM50311506 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_622957 (CHEMBL1112209) | ||
| Ki | 253±n/a nM | ||
| Citation |  Palin, R; Clark, JK; Evans, L; Feilden, H; Fletcher, D; Hamilton, NM; Houghton, AK; Jones, PS; McArthur, D; Montgomery, B; Ratcliffe, PD; Smith, AR; Sutherland, A; Weston, MA; Wishart, G Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. Bioorg Med Chem Lett19:6441-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
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| BDBM50311506 | |||
| n/a | |||
| Name | BDBM50311506 | ||
| Synonyms: | CHEMBL1087277 | N-methyl-2-(2-oxo-3-(1-(4-phenylcyclohexyl)piperidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H34N4O2 | ||
| Mol. Mass. | 446.5845 | ||
| SMILES | CNC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2CCC(CC2)c2ccccc2)c1=O |(34.22,-20.61,;32.68,-20.6,;31.9,-21.92,;33.26,-22.63,;30.36,-21.91,;29.58,-23.24,;28.11,-23.72,;26.78,-22.95,;25.45,-23.72,;25.44,-25.27,;26.78,-26.04,;28.11,-25.26,;29.58,-25.73,;30.35,-27.07,;29.58,-28.4,;30.34,-29.72,;31.88,-29.73,;32.65,-28.39,;31.88,-27.05,;32.65,-31.06,;31.87,-32.39,;32.63,-33.72,;34.17,-33.73,;34.95,-32.39,;34.19,-31.05,;34.94,-35.06,;34.16,-36.39,;34.92,-37.73,;36.46,-37.74,;37.24,-36.4,;36.47,-35.07,;30.48,-24.49,;32.02,-24.49,)| | ||
| Structure | 
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