| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-2 |
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| Ligand | BDBM50187658 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_617801 (CHEMBL1100507) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Arioka, S; Sakagami, M; Uematsu, R; Yamaguchi, H; Togame, H; Takemoto, H; Hinou, H; Nishimura, S Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Bioorg Med Chem18:1633-40 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-2 |
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| Name: | Sialidase-2 |
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| Synonyms: | Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960638 |
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| Residue: | 380 |
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| Sequence: | MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYD
APTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRAN
VTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYA
YRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHL
RARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH
SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYE
EIVFLMFTLKQAFPAEYLPQ
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| BDBM50187658 |
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| n/a |
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| Name | BDBM50187658 |
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| Synonyms: | 4',5-dihydroxy-7-methoxy flavone | 4',5-dihydroxy-7-methoxyflavone | 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one | 7-O-methylapigenin | CHEMBL210635 | Gonkwanin | genkwanin |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12O5 |
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| Mol. Mass. | 284.2635 |
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| SMILES | COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)cc1 |
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| Structure | 
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