| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50312961 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_616079 (CHEMBL1102042) |
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| Ki | 39±n/a nM |
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| Citation |  Eastwood, P; Gonzalez, J; Paredes, S; Nueda, A; Domenech, T; Alberti, J; Vidal, B Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists. Bioorg Med Chem Lett20:1697-700 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50312961 |
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| n/a |
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| Name | BDBM50312961 |
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| Synonyms: | CHEMBL1081038 | N-(2-(4-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopropanecarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16FN3O |
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| Mol. Mass. | 333.3589 |
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| SMILES | Fc1ccc(cc1)-c1nc(NC(=O)C2CC2)ccc1-c1ccncc1 |
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| Structure | 
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