| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50312966 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_616400 (CHEMBL1100686) |
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| Ki | 4±n/a nM |
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| Citation |  Eastwood, P; Gonzalez, J; Paredes, S; Fonquerna, S; Cardús, A; Alonso, JA; Nueda, A; Domenech, T; Reinoso, RF; Vidal, B Discovery of potent and selective bicyclic A(2B) adenosine receptor antagonists via bioisosteric amide replacement. Bioorg Med Chem Lett20:1634-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50312966 |
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| n/a |
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| Name | BDBM50312966 |
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| Synonyms: | CHEMBL1081971 | N-(6-(furan-2-yl)-5-(pyrimidin-4-yl)pyridin-2-yl)cyclopropanecarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4O2 |
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| Mol. Mass. | 306.3187 |
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| SMILES | O=C(Nc1ccc(-c2ccncn2)c(n1)-c1ccco1)C1CC1 |
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| Structure | 
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