| Reaction Details |
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 | Report a problem with these data |
| Target | IgG receptor FcRn large subunit p51 |
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| Ligand | BDBM50314093 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_627629 (CHEMBL1114459) |
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| IC50 | 2.6±n/a nM |
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| Citation |  McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Synthesis and structure-activity relationships of dimeric peptide antagonists of the human immunoglobulin G-human neonatal Fc receptor (IgG-FcRn) interaction. J Med Chem53:1587-96 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| IgG receptor FcRn large subunit p51 |
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| Name: | IgG receptor FcRn large subunit p51 |
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| Synonyms: | FCGRN_HUMAN | FCGRT | FCRN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39742.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_627631 |
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| Residue: | 365 |
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| Sequence: | MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
IPATA
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| BDBM50314093 |
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| n/a |
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| Name | BDBM50314093 |
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| Synonyms: | CHEMBL1090631 |
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| Type | Small organic molecule |
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| Emp. Form. | C151H210N40O35S4 |
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| Mol. Mass. | 3273.79 |
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| SMILES | CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O |r| |
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| Structure | 
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