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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mitogen-activated protein kinase 10 | ||
| Ligand | BDBM50314148 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_624060 (CHEMBL1116946) | ||
| Ki | 16±n/a nM | ||
| Citation |  Siddiqui, MA; Reddy, PA Small molecule JNK (c-Jun N-terminal kinase) inhibitors. J Med Chem53:3005-12 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mitogen-activated protein kinase 10 | |||
| Name: | Mitogen-activated protein kinase 10 | ||
| Synonyms: | JNK3 | JNK3A | MAP kinase p49 3F12 | MAPK10 | MK10_HUMAN | Mitogen-Activated Protein Kinase 10 (JNK3) | Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) | Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 | PRKM10 | SAPK1B | Stress-activated protein kinase JNK3 | c-Jun N-terminal kinase 3 (JNK3) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 52586.89 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 464 | ||
| Sequence: |
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| BDBM50314148 | |||
| n/a | |||
| Name | BDBM50314148 | ||
| Synonyms: | CHEMBL1089007 | trans-4-(4-(3-(tetrahydro-2H-pyran-3-yl)-1H-pyrazol-4-yl)pyrimidin-2-ylamino)cyclohexanol | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H25N5O2 | ||
| Mol. Mass. | 343.4234 | ||
| SMILES | O[C@H]1CC[C@@H](CC1)Nc1nccc(n1)-c1cn[nH]c1C1CCCOC1 |r,wU:1.0,wD:4.7,(27.93,-38.08,;26.61,-37.31,;25.27,-38.08,;23.94,-37.31,;23.94,-35.78,;25.26,-34.99,;26.6,-35.77,;22.6,-35.02,;21.27,-35.79,;19.93,-35.03,;18.61,-35.8,;18.61,-37.34,;19.94,-38.11,;21.28,-37.34,;19.94,-39.66,;21.19,-40.56,;20.71,-42.02,;19.17,-42.02,;18.7,-40.56,;17.37,-39.78,;16.04,-40.55,;14.72,-39.77,;14.72,-38.23,;16.07,-37.47,;17.38,-38.24,)| | ||
| Structure | 
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