| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50314514 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624612 (CHEMBL1111572) |
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| Ki | 539000±n/a nM |
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| Citation |  Brown, A; Ellis, D; Wallace, O; Ralph, M Identification of amide bioisosteres of triazole oxytocin antagonists. Bioorg Med Chem Lett20:2224-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM50314514 |
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| n/a |
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| Name | BDBM50314514 |
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| Synonyms: | 5-(2,3-dimethylphenyl)-N-(2-methoxyethyl)-N-(6-methoxypyridin-3-yl)pyrazine-2-carboxamide | CHEMBL1093599 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O3 |
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| Mol. Mass. | 392.451 |
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| SMILES | COCCN(C(=O)c1cnc(cn1)-c1cccc(C)c1C)c1ccc(OC)nc1 |
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| Structure | 
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