| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50315586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_627568 (CHEMBL1113574) |
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| EC50 | >100000±n/a nM |
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| Citation |  Pastorin, G; Federico, S; Paoletta, S; Corradino, M; Cateni, F; Cacciari, B; Klotz, KN; Gao, ZG; Jacobson, KA; Spalluto, G; Moro, S Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process. Bioorg Med Chem18:2524-36 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50315586 |
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| n/a |
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| Name | BDBM50315586 |
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| Synonyms: | 2-(2-Furyl)-5-methylthio-7-phenylacetylamino[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine | CHEMBL1090126 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N6O2S |
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| Mol. Mass. | 366.397 |
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| SMILES | CSc1nc(NC(=O)Cc2ccccc2)n2nc(nc2n1)-c1ccco1 |
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| Structure | 
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