| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50315855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_625530 (CHEMBL1107962) |
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| Ki | 661±n/a nM |
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| Citation |  Narlawar, R; Lane, JR; Doddareddy, M; Lin, J; Brussee, J; Ijzerman, AP Hybrid ortho/allosteric ligands for the adenosine A(1) receptor. J Med Chem53:3028-37 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50315855 |
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| n/a |
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| Name | BDBM50315855 |
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| Synonyms: | CHEMBL1090687 | LUF-6258 | N6-[2-Amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno-[2,3-c]pyridin-6-yl-9-nonyloxy-4-phenyl]-adenosine |
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| Type | Small organic molecule |
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| Emp. Form. | C39H45Cl2N7O6S |
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| Mol. Mass. | 810.789 |
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| SMILES | Nc1sc2CN(CCCCCCCCCOc3ccc(Nc4ncnc5n(cnc45)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)cc3)CCc2c1C(=O)c1ccc(Cl)c(Cl)c1 |r| |
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| Structure | 
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