| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50315864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_625528 (CHEMBL1107960) |
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| EC50 | 3700±n/a nM |
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| Citation |  Narlawar, R; Lane, JR; Doddareddy, M; Lin, J; Brussee, J; Ijzerman, AP Hybrid ortho/allosteric ligands for the adenosine A(1) receptor. J Med Chem53:3028-37 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50315864 |
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| n/a |
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| Name | BDBM50315864 |
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| Synonyms: | 2-Amino-6-[3-(4-nitrophenoxy)-propyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl-(3,4-dichlorophenyl)-methanone | CHEMBL1093487 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21Cl2N3O4S |
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| Mol. Mass. | 506.402 |
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| SMILES | Nc1sc2CN(CCCOc3ccc(cc3)[N+]([O-])=O)CCc2c1C(=O)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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