| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
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| Ligand | BDBM34138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_631990 (CHEMBL1107438) |
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| IC50 | 4700±n/a nM |
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| Citation |  Cheltsov, AV; Aoyagi, M; Aleshin, A; Yu, EC; Gilliland, T; Zhai, D; Bobkov, AA; Reed, JC; Liddington, RC; Abagyan, R Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention. J Med Chem53:3899-906 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptosis regulator Bcl-2 |
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| Name: | Apoptosis regulator Bcl-2 |
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| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
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| Type: | Homodimer or heterodimer |
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| Mol. Mass.: | 26269.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10415 |
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| Residue: | 239 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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| BDBM34138 |
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| n/a |
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| Name | BDBM34138 |
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| Synonyms: | 4,5-dibenzylbenzene-1,2-diol, 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18O2 |
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| Mol. Mass. | 290.3557 |
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| SMILES | Oc1cc(Cc2ccccc2)c(Cc2ccccc2)cc1O |
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| Structure | 
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