| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50316846 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632846 (CHEMBL1112852) |
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| Ki | 21±n/a nM |
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| Citation |  Sirisha, B; Narsaiah, B; Yakaiah, T; Gayatri, G; Sastry, GN; Prasad, MR; Rao, AR Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands. Eur J Med Chem45:1739-45 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50316846 |
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| n/a |
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| Name | BDBM50316846 |
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| Synonyms: | 2-(4-Fluorobenzyl)-3-prop-2-yn-1-yl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one | CHEMBL1088253 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17FN2OS |
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| Mol. Mass. | 352.425 |
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| SMILES | Fc1ccc(Cc2nc3sc4CCCCc4c3c(=O)n2CC#C)cc1 |
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| Structure | 
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