| Reaction Details |
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 | Report a problem with these data |
| Target | Cholinesterase |
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| Ligand | BDBM50119784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_631312 (CHEMBL1105649) |
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| IC50 | >10000±n/a nM |
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| Citation |  Rook, Y; Schmidtke, KU; Gaube, F; Schepmann, D; Wünsch, B; Heilmann, J; Lehmann, J; Winckler, T Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents. J Med Chem53:3611-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholinesterase |
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| Name: | Cholinesterase |
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| Synonyms: | BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase |
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| Type: | Enzyme |
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| Mol. Mass.: | 65643.35 |
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| Organism: | Equus caballus (Horse) |
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| Description: | P81908 |
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| Residue: | 574 |
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| Sequence: | EEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATK
YANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQT
GTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQK
NIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEAR
NRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLT
DMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPR
VSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYY
FEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNP
NGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAE
REWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
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| BDBM50119784 |
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| n/a |
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| Name | BDBM50119784 |
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| Synonyms: | 1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-pyridine;diiodide | CHEMBL104381 | CHEMBL389283 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22N2 |
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| Mol. Mass. | 242.3582 |
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| SMILES | C(CCC[n+]1ccccc1)CC[n+]1ccccc1 |
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| Structure | 
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