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TargetAmine oxidase [flavin-containing] A
LigandBDBM15613
Substrate/Competitorn/a
Meas. Tech.ChEMBL_629407 (CHEMBL1105760)
IC50 361380±n/a nM
Citation Alcaro, S; Gaspar, A; Ortuso, F; Milhazes, N; Orallo, F; Uriarte, E; Yáñez, M; Borges, F Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. Bioorg Med Chem Lett20:2709-12 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] A
Name:Amine oxidase [flavin-containing] A
Synonyms:AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:Protein
Mol. Mass.:59689.53
Organism:Homo sapiens (Human)
Description:P21397
Residue:527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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BDBM15613
n/a
NameBDBM15613
Synonyms:4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | Aurorix | CHEMBL86304 | MCL | Moclobemide
TypeSmall organic molecule
Emp. Form.C13H17ClN2O2
Mol. Mass.268.739
SMILESClc1ccc(cc1)C(=O)NCCN1CCOCC1
Structure
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