| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Ligand | BDBM50318053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_631366 (CHEMBL1109118) |
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| IC50 | 130±n/a nM |
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| Citation |  Zou, XQ; Peng, SM; Hu, CP; Tan, LF; Yuan, Q; Deng, HW; Li, YJ Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin. Bioorg Med Chem18:3020-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldo-keto reductase family 1 member B1 [K65Q] |
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| Name: | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Synonyms: | AKR1B1 | ALDR_BOVIN | Aldose reductase |
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| Type: | Protein |
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| Mol. Mass.: | 35916.27 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P16116[K65Q] |
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| Residue: | 315 |
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| Sequence: | AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQA
KLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKD
FFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPA
VNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKY
NKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACAL
VSCASHRDYPFHEEF
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| BDBM50318053 |
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| n/a |
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| Name | BDBM50318053 |
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| Synonyms: | (5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)methyl 5-(nitrooxy)pentanoate | CHEMBL1095399 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19NO9 |
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| Mol. Mass. | 429.3769 |
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| SMILES | Oc1cc(OCOC(=O)CCCCO[N+]([O-])=O)cc2oc(cc(=O)c12)-c1ccccc1 |
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| Structure | 
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