| Reaction Details |
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 | Report a problem with these data |
| Target | Urotensin-2 receptor |
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| Ligand | BDBM50302274 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_636746 (CHEMBL1167035) |
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| Ki | 6.3±n/a nM |
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| Citation |  Maryanoff, BE; Kinney, WA Urotensin-II receptor modulators as potential drugs. J Med Chem53:2695-708 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urotensin-2 receptor |
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| Name: | Urotensin-2 receptor |
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| Synonyms: | G-protein coupled receptor 14 | G-protein coupled sensory epithelial neuropeptide-like receptor | Gpr14 | Senr | UR-II-R | UR2R_RAT | Urotensin-II | Uts2r |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42725.34 |
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| Organism: | RAT |
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| Description: | Urotensin-II UTS2R RAT::P49684 |
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| Residue: | 386 |
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| Sequence: | MALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSA
MGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGD
VGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLL
TLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWL
SQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNY
LTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSG
RSLSSSSQQATETLMLSPVPRNGALL
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| BDBM50302274 |
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| n/a |
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| Name | BDBM50302274 |
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| Synonyms: | (4R,10bR)-4-(3,4-dimethoxyphenyl)-10-(4-ethylpiperazin-1-yl)-1,2,3,4-tetrahydropyrido[2,1-a]isoindol-6(10bH)-one | CHEMBL566894 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33N3O3 |
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| Mol. Mass. | 435.5585 |
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| SMILES | CCN1CCN(CC1)c1cccc2C(=O)N3[C@H](CCC[C@@H]3c3ccc(OC)c(OC)c3)c12 |r| |
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| Structure | 
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