| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50321786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_641177 (CHEMBL1174684) |
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| Ki | 3.60±n/a nM |
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| Citation |  Oberdorf, C; Schmidt, TJ; Wünsch, B 5D-QSAR for spirocyclic sigma1 receptor ligands by Quasar receptor surface modeling. Eur J Med Chem45:3116-24 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50321786 |
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| n/a |
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| Name | BDBM50321786 |
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| Synonyms: | (R)-1-benzyl-2'-(dimethoxymethyl)-6'-methoxy-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] | CHEMBL1169778 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29NO4S |
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| Mol. Mass. | 403.535 |
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| SMILES | COC(OC)c1cc2c(C[C@H](OC)OC22CCN(Cc3ccccc3)CC2)s1 |r| |
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| Structure | 
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