Reaction Details |
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Target | Metallo-beta-lactamase L1 type 3 |
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Ligand | BDBM50322610 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_641774 (CHEMBL1177097) |
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Ki | 32000±n/a nM |
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Citation | Lassaux, P; Hamel, M; Gulea, M; Delbrück, H; Mercuri, PS; Horsfall, L; Dehareng, D; Kupper, M; Frère, JM; Hoffmann, K; Galleni, M; Bebrone, C Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases. J Med Chem53:4862-76 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Metallo-beta-lactamase L1 type 3 |
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Name: | Metallo-beta-lactamase L1 type 3 |
Synonyms: | BLA1_STEMA | Beta-lactamase L1 |
Type: | PROTEIN |
Mol. Mass.: | 30803.13 |
Organism: | Stenotrophomonas maltophilia |
Description: | ChEMBL_1500319 |
Residue: | 290 |
Sequence: | MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLT
ALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRR
TGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAG
HTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCD
VLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
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BDBM50322610 |
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n/a |
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Name | BDBM50322610 |
Synonyms: | CHEMBL1170424 | alpha-Sulfanylbenzylphosphonic acid |
Type | Small organic molecule |
Emp. Form. | C7H9O3PS |
Mol. Mass. | 204.183 |
SMILES | OP(O)(O)C(=S)c1ccccc1 |
Structure |
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