| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50254264 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_644535 (CHEMBL1211412) |
|---|
| Ki | 836±n/a nM |
|---|
| Citation |  Cheng, F; Xu, Z; Liu, G; Tang, Y Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. Eur J Med Chem45:3459-71 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM50254264 |
|---|
| n/a |
|---|
| Name | BDBM50254264 |
|---|
| Synonyms: | 3-(2-Fluorobenzyl)-7-(2-oxazolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine | 3-(2-fluorobenzyl)-7-(oxazol-2-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | CHEMBL468701 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10FN7O |
|---|
| Mol. Mass. | 311.2739 |
|---|
| SMILES | Nc1nc(-c2ncco2)c2nnn(Cc3ccccc3F)c2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
