| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ornithine decarboxylase |
|---|
| Ligand | BDBM50005727 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_643973 (CHEMBL1211872) |
|---|
| IC50 | 39±n/a nM |
|---|
| Citation |  Klee, N; Wong, PE; Baragaña, B; Mazouni, FE; Phillips, MA; Barrett, MP; Gilbert, IH Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif. Bioorg Med Chem Lett20:4364-6 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ornithine decarboxylase |
|---|
| Name: | Ornithine decarboxylase |
|---|
| Synonyms: | DCOR_RAT | Odc | Odc1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51037.04 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1344641 |
|---|
| Residue: | 461 |
|---|
| Sequence: | MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALP
RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQI
KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL
LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPG
SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ
TGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC
DGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQI
QSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
|
|
|
|---|
| BDBM50005727 |
|---|
| n/a |
|---|
| Name | BDBM50005727 |
|---|
| Synonyms: | 1-Amino-3-aminooxy-propan-2-ol | CHEMBL26857 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C3H10N2O2 |
|---|
| Mol. Mass. | 106.1237 |
|---|
| SMILES | NCC(O)CON |
|---|
| Structure | 
|
|---|
Search and Browse
