| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 1B1 |
|---|
| Ligand | BDBM50325673 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_652515 (CHEMBL1225718) |
|---|
| IC50 | 1024±n/a nM |
|---|
| Citation |  Takemura, H; Itoh, T; Yamamoto, K; Sakakibara, H; Shimoi, K Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Bioorg Med Chem18:6310-5 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 1B1 |
|---|
| Name: | Cytochrome P450 1B1 |
|---|
| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60861.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1474523 |
|---|
| Residue: | 543 |
|---|
| Sequence: | MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI
GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF
ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL
LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL
VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA
EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL
DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV
FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL
FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE
TCQ
|
|
|
|---|
| BDBM50325673 |
|---|
| n/a |
|---|
| Name | BDBM50325673 |
|---|
| Synonyms: | 5,7-dihydroxy-4'-methoxyflavanone | CHEMBL470266 | ISOSAKUTANETIN | isosakuranetin | naringenin 4'-methyl ether |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14O5 |
|---|
| Mol. Mass. | 286.2794 |
|---|
| SMILES | COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
