| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1B1 |
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| Ligand | BDBM50241084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_652515 (CHEMBL1225718) |
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| IC50 | 20±n/a nM |
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| Citation |  Takemura, H; Itoh, T; Yamamoto, K; Sakakibara, H; Shimoi, K Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Bioorg Med Chem18:6310-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1B1 |
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| Name: | Cytochrome P450 1B1 |
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| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60861.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1474523 |
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| Residue: | 543 |
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| Sequence: | MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI
GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF
ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL
LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL
VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA
EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL
DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV
FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL
FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE
TCQ
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| BDBM50241084 |
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| n/a |
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| Name | BDBM50241084 |
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| Synonyms: | 3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyflavone | 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone | 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one | 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one | CHEMBL214321 | Chryseriol | Chrysoeriol | Chrysoeriol (26) | Luteolin 3'-methyl ether | cid_5280666 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12O6 |
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| Mol. Mass. | 300.2629 |
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| SMILES | COc1cc(ccc1O)-c1cc(=O)c2c(O)cc(O)cc2o1 |
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| Structure | 
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