| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM50325744 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_652614 (CHEMBL1225817) |
|---|
| Ki | 46±n/a nM |
|---|
| Citation |  Jean, M; Renault, J; Levoin, N; Danvy, D; Calmels, T; Berrebi-Bertrand, I; Robert, P; Schwartz, JC; Lecomte, JM; Uriac, P; Capet, M Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands. Bioorg Med Chem Lett20:5376-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 51511.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35348 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
|
|
|
|---|
| BDBM50325744 |
|---|
| n/a |
|---|
| Name | BDBM50325744 |
|---|
| Synonyms: | CHEMBL1223683 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)quinolin-2-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26Cl2N4 |
|---|
| Mol. Mass. | 429.385 |
|---|
| SMILES | Clc1cccc(N2CCN(CCCCNc3ccc4ccccc4n3)CC2)c1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
