| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine deaminase |
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| Ligand | BDBM82009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_652430 (CHEMBL1225633) |
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| Ki | 1960±n/a nM |
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| Citation |  Fernández, JR; Sweet, ES; Welsh, WJ; Firestein, BL Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine. Bioorg Med Chem18:6748-55 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Guanine deaminase |
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| Name: | Guanine deaminase |
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| Synonyms: | GAH | GDA | GUAD_HUMAN | Guanase | Guanine aminase | Guanine aminohydrolase | KIAA1258 | p51-nedasin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50993.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_885179 |
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| Residue: | 454 |
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| Sequence: | MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF
KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA
EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY
KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH
ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH
CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE
KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI
SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
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| BDBM82009 |
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| n/a |
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| Name | BDBM82009 |
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| Synonyms: | CAS_1188 | CHEMBL1424 | NSC_1188 | Xanthine |
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| Type | Small organic molecule |
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| Emp. Form. | C5H4N4O2 |
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| Mol. Mass. | 152.1109 |
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| SMILES | O=c1[nH]c2nc[nH]c2c(=O)[nH]1 |
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| Structure | 
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