Reaction Details |
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Target | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
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Ligand | BDBM24778 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_654655 (CHEMBL1243699) |
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IC50 | 290000±n/a nM |
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Citation | Love, KR; Catic, A; Schlieker, C; Ploegh, HL Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat Chem Biol3:697-705 (2007) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
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Name: | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
Synonyms: | Neuron cytoplasmic protein 9.5 | PGP 9.5 | PGP9.5 | UCH-L1 | UCHL1 | UCHL1_HUMAN | Ubiquitin thioesterase L1 |
Type: | PROTEIN |
Mol. Mass.: | 24819.03 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_974327 |
Residue: | 223 |
Sequence: | MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE
NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE
TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP
FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
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BDBM24778 |
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n/a |
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Name | BDBM24778 |
Synonyms: | 2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-methyl-1,4-naphthoquinone, 5 | CHEMBL590 | Menadione | Menadione (5d) | Menadione (Vitamin K3) | Menadione, 9 | Vitamin K3 | cid_4055 |
Type | Small organic molecule |
Emp. Form. | C11H8O2 |
Mol. Mass. | 172.18 |
SMILES | CC1=CC(=O)c2ccccc2C1=O |t:1| |
Structure |
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